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Spurs made some interesting signings this summer with Matt Doherty and Pierre-Emile Hojbjerg joining, although they still remain without a real back-up for Harry Kane after loaning youngster Troy Parrott out to Millwall.
The Toffees also made some eye-catching moves in the transfer market, not least the high-profile capture of James Rodriguez from Real Madrid, and will be hoping to begin in positive fashion against a side they have not beaten since 2012.
Giovani Lo Celso is the hosts' major concern ahead of the season-opener, with the Argentina internationalhaving been absent for most of pre-season.
Everton have some doubts in defence, with Mason Holgate and Yerry Mina both likely to miss out, meaning a possible debut for youngster Lewis Gibson.
Much of the attention on this game will surely be focused on James Rodriguez, with his signing certainly sendingout a message that the Toffees are intent on seriously improving their 12th place finish from last term.
The Colombian should provide some world-class service into the box for Everton's forwards, something that was missing from Carlo Ancelotti's side last season.
Indeed, Everton's matches last season averaged 2.63 goals -one of the lowest totals in the division -with 20 of their games seeing less than three goals scored.
Spurs, though,conceded just 17 home goals last term, with only four teams shipping fewer, and the Tottenham Hotspur Stadium remains a tough place to visit.
Both games between these two sides in the previous campaigns were tight, low-scoring affairs and backing a similar clash on Sunday makes sense.
Odds correct at the time of writing. Please gamble responsibly.